lapatinib will boost the degree or influence of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.chloramphenicol will raise the amount or effect of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.erythromycin ethylsuccinate will enhance the degree or effect of bortezomib